The Gifted fits into the overall X-Men universe from the Marvel Comics and Fox films, but allows the audience to see a smaller more intimate view of what it would look like for a family to discover their gifts for the first time.
Reed Strucker (Stephen Moyer) works for Sentinel Services, but when his children, Lauren (Natalie Alyn Lind) and Andy (Percy Hynes White), display their powers, the family suddenly goes on the run from the government. Fortunately, there are others with gifts, called mutants, who have formed a sort of Underground Railroad to protect those with gifts from persecution. Marco Diaz AKA Eclipse (Sean Teale) heads up the mutant uprising, alongside his girlfriend Lorna Dane AKA Polaris (Emma Dummont), a ripped-from-the-comics character who is also the daughter of Magneto. [Other mutants who feature in the show, from the comics, are Blink, Sage, Thunderbird, Beautiful Dreamer, the Von Struckers AKA Fenris, and the Frost triplets AKA the Stepford Cuckoos.]